This quote delves into the complexities of emotions in relationships, particularly highlighting the significance of frustration and upset as indicators of care and investment. The phrase "when a woman no longer gets frustrated and upset with you" suggests that these emotional reactions are signs of her emotional investment in the relationship and her feelings towards the other person. When a woman deeply cares for someone, she may get frustrated or upset at times because she is emotionally invested in the relationship's well-being and wants it to succeed. However, as the quote continues, "you can almost guarantee that she doesn't care anymore," it implies that the absence of these emotional responses may signal a shift in her feelings or a decrease in her level of investment in the relationship. It suggests that when a woman stops expressing frustration or upset, it may indicate a loss of interest or emotional detachment. It is essential to note that each person's emotional expression varies, and the absence of frustration or upset does not necessarily mean she does not care at all, as emotions can be complex and multifaceted. However, the quote serves as a reminder that emotional responses and expressions are vital aspects of human connections, reflecting the depth of one's feelings and care for another.