This statement reflects the natural ebb and flow of relationships in life. It suggests that people enter and exit our lives, but the most meaningful and lasting connections are the ones that endure and stay.
The phrase "People come and people go" acknowledges the transient nature of some relationships, as individuals may come into our lives for various reasons and periods of time.
However, the statement also emphasizes the significance of those who remain, stating "The best will stay." It implies that the strongest and most valuable relationships are the ones that withstand the test of time and adversity.